Interesting review article on natural products that can interact with the cannabinoid receptors:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931553/
Interesting indeed but a difficult read for me. I guess I lack the scientific background to make it understandable even trying to absorb meaning through context!
Thanks for a meaningful and informative post though. Despite my stumbling blocks this is relevant to my interests 🙂
In summary, in this researcher’s opinion, after searching the r&d going on with cannibinoids and CB receptors, there are not too many other sources of CB1 agonists known other than from Cannibis species but there are a couple possible other places to look. Most of the CB agonists found in nature tend to be more related to CB2 agonists, which are theraputically more active in pain and immume system regulation. Further, ther are a few Fatty acid hydrolase (FAAH) inhibitors in nature that are known to slow the destruction of endogenous, or built in endocannibanoids that can act on both CB1 and CB2 receptor sites, meaning there are some nattys that have recreational value by manipulating how your body uses its’ built in cannibanoids.
More research is needed and more research is being done by both big pharma and universities.